News

Congratulations to Andrew who has been awarded $900,000 in the NHMRC Ideas Grants for his project “Advancing cluster randomised trials to the next generation: Development of multi-domain platform cluster trial designs and machine learning methods for estimating personalised treatment effects”.

The project will explore complex cluster randomisation approaches in already complex adaptive multidomain platform trials. Currently, the existing underlying statistical framework for these trial designs only allows for randomisation of individuals, not of clusters, and a novel statistical framework is needed.

Andrew’s team, the “cluster cluster”, will develop a new set of clinical trial designs that enable multiple different trials to be conducted simultaneously in the same set of individuals, even when some trials involve cluster randomisation and others individual randomisation. Machine learning methods will be developed so that the characteristics of individuals who benefit most from the treatments are determined. This work will enable treatment policies to be efficiently assessed, thereby enabling better healthcare.

Congratulations Andrew on this success, and we look forward to seeing the outputs at one of our meetings soon!